Dr. Eng., Lecturer NationalAcademy of Sciences- Sofia, Bolgaria.
Vasil Lyubenov Kanisov
Kanisov V.L, (2022). Quantum Method of Pharmacological studies of Biologically active substances (bav) of Medicinal plants with Antiviral and Endothelioprotective Properties. Pharmacy and Drug Development. 1(1). DOI: 10.58489/2836-2322/004
© 2022 Vasil Lyubenov Kanisov, this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
medicinal plant, yellow color, quantum technique, medical characteristic
In this work, a comprehensive study of all medicinal plants with the yellow color of flowers is carried out. This morphologically valuable feature is color, associated with electromagnetic radiation (absorption), as the main factor in the formation of secondarymetabolites (BAV). As a resultof comparative analysisand quantum researchmethodology, we identified plant species that have a characteristic therapeutic characteristic - antiviral and have endothelioprotective properties.
The specific characteristics of the metabolism of various plant species have determined their selective ability to accumulate chemicalsthat have high physiological activity at low concentrations - the so-called Biologically active substances (BAS). The physiological activity of substances can be considered both from the point of view of the possibility of their pharmacological study and medical use [1] , and from the point of view of maintaining the normal functioning of the human body [2] or giving a group of organisms special properties [3]. For example, flavicin (natural flavonoids) possessing endothelialprotective properties [4].
Secondary metabolites are the most important physiologically active compounds in the plant world. Their number, investigated by pharmacological science, is increasing every year. At the moment, only about 15% of all plant species have been studied for the presence of these substances.
Compounds of secondary metabolism, unlike primary metabolites, have functional significance not only at the level of the cell, but at the level of the tissue and cell of the whole plant. Most often, these substances perform "ecological" functions, i.e., protect the plant from various pests and pathogens, participate in the reproduction of plants, giving color and smell to flowers. and fruits, provide interaction of plants with each other and with other organisms in the ecosystem.
In this particular case, we consider flavonoids as compounds of secondary metabolism in the plant. The natural functions of flavonoids are poorly understood. It was assumed that due to the ability to absorb ultraviolet radiation (330-350 nm) and part of the visible light (520-560 nm), they protect plant tissues from excess radiation. In mammals, flavonoids are able to change the activity of many metabolic enzymes [5].
It has been established that in the irus SARS-CoV-2 is sensitive to ultraviolet irradiation with a dose of at least 25 mJ / cm2 [6] In this range, absorption of ultraviolet light by a medicinal plant with yellow light is observed.
Numerous studies on the study of angioprotective and antioxidant properties of natural flavonoids, including diabetic micro- and microangiopathy, have revealed that flavonoids are among the promising groups with endothelialprotective effects. [7].
The aim of our study was to study the effect of flower color as specific characteristics of the metabolism of different plant species, which determined their ability to accumulate the chemicalM, the main flavonoid. Which flavonoids, in turn, have specific pharmacological properties.
The object of the study was any medicinal plants with a yellow color of flowers, as well as yellow - yellow, with the addition of a different color. Yellow - colors of electromagnetic radiation with wavelengths from 550 to 590 nm [8]
We take electromagnetic radiation (absorption) as the main factor in the formation of secondary metabolites, to which we apply the Quantum Research Methodology.
According to the special theory of relativity (SRT), there is a connection between mass and energy, expressed by Einstein's famous formula:
{\displaystyle E=mc^{2},} (1)
Where: {\displaystyle E} is the energy of the system; {\displaystyle m} is its mass; {\displaystyle c} is the speed of light in a vacuum.
In a vacuum, the energy and momentum of a photon depend only on its frequency ( {\displaystyle \nu } equivalent, on the wavelength {\displaystyle \lambda =c/\nu }):
(2)
Where: - Photon (light) energy; - Planck's constant (6.624. 10-34 j.s); - Wave frequencies
I consider the mass () of a photon (officially, a term that goes out of use in quantum physics) to be equal to:
(3) See: Table 1 [9]
The pressure of electromagnetic radiation, the pressure of light () is the pressure exerted by light (and in general electromagnetic) radiation incident on the surface of a body. [9]
The pressure of electromagnetic radiation [10] is a consequence of the fact that it, like any material object with energy and moving at speed, also has a momentum: .
And since for electromagnetic radiation,
Experimentally, light pressure was first studied by P. N. Lebedev in 1899. In electrodynamics, the pressure of electromagnetic radiation is described Results And Discussion According to the formula (1), (2) and (3), we will compile Table 1. From Table 1 - row "Color" "Yellow" we will make Table 2. Table 1 - Correspondences of lengths, frequencies, mass and energy of electromagnetic radiation and colors. Color Wavelength range (λ), [nm] Wave frequency range(ν), [Hz]1. 1014 Range Mass of photons (m) [kg]1. 10-36 Photon energy range (E) [eV] Infrared 770 - 40 000 < 3> 2,206 - 0,3577 < 1> Red 625- 740 4,05-4,8 3,52 - 2,99 1,68 - 1,98 Orange 590 -625 4,8-5,1 3,74-3,52 1,98 - 2,10 Yellow 565 – 590 5,1-5,3 3,89-3,74 2,10 - 2,19 Green 500 – 565 5,3-6,0 4,14-3,89 2,19 - 2,48 Blue 485 – 500 6,0-6,2 4,56-4,14 2,48 - 2,56 Blue 440 – 485 6,2-6,8 5,01-4,56 2,56 - 2,82 Violet 380 – 440 6,8-7,9 5,81-5,01 2,82 - 3,26 Ultraviolet 0,1- 400 2,998.104- 7,50 22 071,1 – 5,511 12 398–3,1 Table 2 - A complete list of plants with yellow flower flowers Latin Name Latin Name 67. Melilotus officinalis (L.) Pall. Prangos 16. Brassica (Sinapis) nigra Koch Zherushnik Pyrenees Jaundice spreading 35. Erysimum repandum L. Jaundice notched-toothed 1. Biologically active substances (BAV) of all medicinal plants Table 2, have high pharmacological antiviral, bactericidal, anti-inflammatory, antiseptic and insecticidal activity. 2. Looking at the equations (4), (5), (6), and (7) it turned out that the plants emitted yellow color of the flowers (in the energy range: 2.10 - 2.19 eV) absorb infrared light (in the energy range: < 1>), which light possesses some properties like: increasing the diameter of the vessels and improving blood circulation (improving endothelial function); activation of cellular immunity (antiviral activity) ; removal of tissue swelling and inflammation (improvement of endothelial function); relief of pain syndromes; improvement of metabolism; removal of emotional stress; restoration of water-salt balance; normalization of hormonal levels. 3. Quantum mechanisms and biological structures are related – their properties are uniform and/or supplemented. This connection can be established by creating a mathematical-physical-biological model, and in the future by studying their pharmacodynamic and pharmacokinetic properties, and behavior, through this model In this work,a comprehensive study of all medicinal plantswith yellow flowersis carried out. This morphologically valuable feature is color, associated with electromagnetic radiation (absorption), as the main factor in the formation of secondary metabolites. As a result of comparative analysis and quantum research methods, we have identified plant species that have the same therapeutic characteristics. 1. Achillea clypeolata S.S. Yarrow yellow shield-shaped) 60. Jasminum fruticans L. Jasmine shrub 2. Adonis vernalis L. Adonis spring 61. Kickxia spuria (L.) Dum. Kixia real 3. Agrimonia eupatoria L.
Common turnip62. Lactuca serriola L. Compass lettuce 4. Ajuga chamaepitys (L.) Schreb. Tenacious elut 63. Lathyrus pratensis L. Meadow chin 5. Anemone ranunculoides L. Buttercup windmill 64. Lepidium perfoliatum L. Pierced bedbug 6. Anethum graveolens L. Garden dill 65. Linaria vulgaris Mill. Common flaxseed 7. Anthemis tinctoria L. Pupavka dye 66. Lotus corniculatus L. Lyadvenets horned 8. Anthyllis would violate L. Common ulcer Donnik officinalis 9. Aristolochia clematitis L. Kirkazon 68. Oenothera biennis L. Biennial donkey 10. Artemisia absinthium L. Wormwood 69. Parsnip sativa L. Parsnip 11. Asparagus officinalis L.* Pharmacy asparagus 70. Potentilla anserina L. Goose lapchatka 12. Astragalus glycyphyllos L. Astragalus sweet-leaved 71. Potentilla erecta L. Lapchatka erecta 13. Barbarea vulgaris R. Br. Common meadowsweet 72. Potentilla reptans L. Creeping lapchata 14. Berberis vulgaris L. Common barberry 73. Prangos ferulacea (L.) Lindl. 15. Bidens tripartite L. Three-part series 74. Primula etalior Hill. Primrose tall Black mustard 75. Primula vulgaris Huds. (P. acaulis Jacq.) Common primrose 17. Brassica juncea (L.) Czern. et Coss. Sarepta mustard 76. Primula veris L. (P. officinalis Jacq.) Spring primrose 18. Bryonia alba L. Step white 77. Pulicaria vulgaris Gaertn. Bloshnica 19. Bupleurum rotundifolium L. Round-leaved volodushka 78. Radiola rosea L. Radiola pink 20. Caltha palustris L. Swamp koluzhnitsa 79. Ranunculus acris L. Buttercup caustic 21. Carthamus lanatus L. Woolly Safflower 80. Ranunculus repens L. Creeping buttercup 22. Cerinthe minor L. Small waxer 81. Ranunculus would be L. (It would be verna Huds.) Chistyak 23. Chelidonium majus L. Celandine large, warthog 82. Reseda luteola L. Reseda dye, cerva 24. Chrisosplenium alternifollum L. Common spleen 83. Reseda lutea L. Reseda yellow 25. Cnicus benedictus L. Cnikus blessed 84. Rhinanthus minor L. Small rattle 26. Colutea arborescens L. Tree bladderwort 85. Rorippa pyrenaica (L.) Rchb. 27. Cornu’s mas L. Common dogwood 86. Rubia tinctorum L. Madder dye 28. Cotinus purpose coggygria. Leather mackerel 87. Graveolens route L. Fragrant rue 29. Descurainia sofia (L.) Webb. Discurainiia of Sofia 88. Salix alba L. White willow, vetla, whitewash 30. Digitalis grandiflora Mill. Large-flowered bridge 89. Salix fragilis L. Willow brittle 31. Digitalis lanata Ehrh. Woolly obere 90. Sambucus racemosa L. Elderberry tassel 32. Doronicum columnae Ten. Doronicum 91. Scabiosa columbaria L. Scabiosa pigeon 33. Erysimum diffusium Ehrh. 92. Sedum acre L. Ochitok caustic 34. Erysimum crepidifolium Rchb. Jaundice toothed 93. Sedum maximum Suter Big spruce, hare cabbage 94. Senecio nemorensis L. Oak crossbill 36. Euphorbia cyparissias L. Milkweed cypress 95. Senecio jacobaea L. Jacob's Cross 37. Filago arvensis L. Field toad 96. Senecio vulgaris L. Common crossbill 38. Filago vulgaris Lam. Small toad 97. Sempervivum ruthenicum Schn. Molodilo Russkoe 39. Foeniculum vulgare Mill. Fennel vulgaris 98. Sideritis montana L. Zheleznitsa gornaya 40. Galium verum L. Real underbrush 99. Sideritis scardica Grsb. Railway 41. Galium cruciatum Purpose. Cruciform underbrush 100. Silena otites (L.) Wibel. Smolevka long-eared 42. Genista tinctoria L. Woodwax 101. Sisymbrium officinale (L.) Purpose. Gulyavnik officinalis 43. Genista segittalis L. Drock lancet 102. Solidago virgaurea L. Common goldenrod 44. Gentiana lutea L. Gentian yellow 103. Stachys straight L. Chisel Straight 45. The dotted gentian L. Pinpoint gentian 104. Stachys annua L. Annual cleaner 46. Geum montanum L. Mountain gravilate 105. Tanacetum vulgare L. Feverfew maiden, golden-flower maiden 47. Geum urbanum L. Urban Gravilate 106. Taraxacum officinale Webber Pharmacy dandelion 48. Glaucium flavum Cr. Glaucium yellow 107. Telekia speciosa Bmg. Telekia the Beautiful 49. Gnaphalium uliginosum L. Sushenitsa topyana 108. Tilia grandifolia Ehrh. Linden heart-leaf 50. Helychrisum arenarium Moench Sandy cumin 109. Tilia parvifolia Ehrh. Small-leaved linden 51. Heracleum sibiricum L. Hogweed 110. Tilia tomentosa Moench Lime pushy, lime voylocha 52. Hieracium pilosella L. Hairy hawk 111. Thalictrum minus L. Basilisk minor 53. Hyoscyamus niger L. Black belena 112. Tragopogon pratensis L. Meadow goat 54. Hypericum perforatum L. St. John's wort perforated 113. Tribulus terrestris L. Tribulus creeping 55. Hypochaeris maculata L. Speckled grouse 114.Tussilago farfara L. Coltsfoot 56. Inula germanica L. Elecampane Germanic 115. Verbascum phlomoides L. Woolly mullein 57. Inula britannica L. Elecampane British 116. Verbascum thapsiforme Schrad. Tupsoid mullein, tall mullein 58. Inula helenium L. Elecampane high 117. Veratrum album L.* Chemerica white 59. Iris pseudacorus L* Yellow killer whale 118. Viscum album L. White mistletoe Findings
Summary